发明申请
US20070027160A1 Piperazine-piperidine antagonists and agonists of the 5-HT1A receptor
失效
哌嗪 - 哌啶拮抗剂和5-HT1A受体的激动剂
- 专利标题: Piperazine-piperidine antagonists and agonists of the 5-HT1A receptor
- 专利标题(中): 哌嗪 - 哌啶拮抗剂和5-HT1A受体的激动剂
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申请号: US11450942申请日: 2006-06-09
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公开(公告)号: US20070027160A1公开(公告)日: 2007-02-01
- 发明人: Magda Asselin , George Grosu , Annmarie Sabb , Wayne Childers , Lisa Havran , Zhongqi Shen , James Bicksler , Dan Chong
- 申请人: Magda Asselin , George Grosu , Annmarie Sabb , Wayne Childers , Lisa Havran , Zhongqi Shen , James Bicksler , Dan Chong
- 申请人地址: US NJ Madison
- 专利权人: Wyeth
- 当前专利权人: Wyeth
- 当前专利权人地址: US NJ Madison
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; C07D403/14
摘要:
The present invention relates to novel piperazine-piperidine compounds. The compounds are useful as 5-HT1A binding agents, particularly as 5-HT1A receptor antagonists and agonists. These compounds are useful in treating central nervous system disorders, such as cognition disorders, anxiety disorders, depression and sexual dysfunction.