发明申请
- 专利标题： Indol-3-y-carbonyl-piperidin and piperazin-derivatives
- 专利标题（中）： 吲哚-3-基羰基 - 哌啶和哌嗪衍生物
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申请号： US11492312申请日： 2006-07-25
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公开(公告)号： US20070027163A1公开(公告)日： 2007-02-01
- 发明人: Caterina Bissantz , Christophe Grundschober , Hasane Ratni , Mark Rogers-Evans , Patrick Schnider
- 申请人： Caterina Bissantz , Christophe Grundschober , Hasane Ratni , Mark Rogers-Evans , Patrick Schnider
- 优先权： EP05107044.9 20050729; EP05111072.4 20051122
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61K31/454 ; A61K31/4439 ; C07D403/02
摘要：
The present invention relates to indol-3-yl-carbonyl-piperidin and piperazin derivatives which act as V1a receptor antagonists and which are represented by Formula I: wherein the residues R1 to R3 are as defined herein. The invention also relates to pharmaceutical compositions containing such compounds, and methods for preparation of the compounds and compositions. The invention further relates to methods for treating dysmenorrhea, hypertension, chronic heart failure, inappropriate secretion of vasopressin, liver cirrhosis, nephrotic syndrome, obsessive compulsive disorder, anxiety and depressive disorders.
公开/授权文献
- US07781436B2 Indol-3-y-carbonyl-piperidin and piperazin-derivatives 公开/授权日：2010-08-24
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