发明申请
- 专利标题： Anti-CCR5 antibody
- 专利标题（中）： 抗CCR5抗体
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申请号： US11581945申请日： 2006-10-16
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公开(公告)号： US20070031408A1公开(公告)日： 2007-02-08
- 发明人: William Olson , Paul Maddon , Naoya Tsurushita , Paul Hinton , Maximillano Vasquez
- 申请人： William Olson , Paul Maddon , Naoya Tsurushita , Paul Hinton , Maximillano Vasquez
- 专利权人： Progenics Pharmaceuticals Inc.,Protein Design Labs, Inc.
- 当前专利权人： Progenics Pharmaceuticals Inc.,Protein Design Labs, Inc.
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; C07K16/28 ; C07K16/10
摘要：
The invention is directed an anti-CCR5 antibody which comprises (i) two light chains, each light chain comprising the expression product of a plasmid designated pVK:HuPRO14O-VK (ATCC Deposit Designation PTA-4097), and (ii) two heavy chains, each heavy chain comprising an expression product of either a plasmid designated pVgl:HuPRO140 HG2-VH (ATCC Deposit Designation PTA-4098) or a plasmic designated pVgl:HuPRO140 (mutB+D+I)-VH (ATCC Deposit Designation PTA-4099) or a fragment thereof which binds to CCR5 on the surface of a human cell.
公开/授权文献
- US07666419B2 Anti-CCR5 antibody 公开/授权日：2010-02-23
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