发明申请
- 专利标题： Pyrazolidinedione derivatives
- 专利标题（中）： 吡唑烷二酮衍生物
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申请号： US10562623申请日： 2004-06-16
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公开(公告)号： US20070037846A1公开(公告)日： 2007-02-15
- 发明人: Heinz Fretz , Thomas Giller , Kurt Hilpert , Olivier Houille , Markus Riederer , Oliver Valdenaire
- 申请人： Heinz Fretz , Thomas Giller , Kurt Hilpert , Olivier Houille , Markus Riederer , Oliver Valdenaire
- 申请人地址： CH Allschwil CH-4123
- 专利权人： ACTELION PHARMACEUTICALS, LTD.
- 当前专利权人： ACTELION PHARMACEUTICALS, LTD.
- 当前专利权人地址： CH Allschwil CH-4123
- 优先权： WOPCT/EP03/06616 20030624
- 国际申请： PCT/EP04/06471 WO 20040616
- 主分类号： A61K31/4152
- IPC分类号： A61K31/4152 ; A61K31/4709 ; A61K31/416
摘要：
The present invention relates to compounds of alkylidene pyrazolidinedione derivatives, which are effective platelet ADP receptor antagonists that prevent platelet aggregation and thrombosis. Thus, the present invention also relates to pharmaceutical compositions that contain the compounds as well as methods of preventing or treating peripheral, visceral, hepatic, renal, cardio- and cerebro-vascular diseases and conditions that are associated with platelet aggregation, including thrombosis, in humans and other mammals. The present invention further provides a process for manufacturing the alkylidene pyrazolidinedione derivatives.
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