发明申请
US20070043029A1 11-Phenyl-dibenzodiazepine derivatives as rxr-antagonists
失效
11-苯基 - 二苯并二氮杂衍生物作为rxr-拮抗剂
- 专利标题： 11-Phenyl-dibenzodiazepine derivatives as rxr-antagonists
- 专利标题（中）： 11-苯基 - 二苯并二氮杂衍生物作为rxr-拮抗剂
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申请号： US10550776申请日： 2004-04-08
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公开(公告)号： US20070043029A1公开(公告)日： 2007-02-22
- 发明人: Junichi Sakaki , Kazuhide Konishi , Masashi Kishida , Masaaki Kimura , Hidefumi Uchiyama , Hironobu Mitani
- 申请人： Junichi Sakaki , Kazuhide Konishi , Masashi Kishida , Masaaki Kimura , Hidefumi Uchiyama , Hironobu Mitani
- 优先权： GB0308335.9 20030410
- 国际申请： PCT/EP04/03806 WO 20040408
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; C07D243/02
摘要：
The present invention relates to novel benzodiazepine compounds exhibiting RXR-antagonist efficacy, for delaying progression of, preventing or treating a condition or disease being associated with RXR-antagonism, in particular selected from diabetes, complication of diabetes such as retinopathy, nephropathy, neuropathy, and hyperlipidemia, obesity, dyslipidemia, and osteoporosis.
公开/授权文献
- US07709470B2 11-phenyl-dibenzodiazepine derivatives as RXR-antagonists 公开/授权日：2010-05-04