A child resistant, senior friendly packaging system is designed to securely hold multiple unit dose products and formed out of natural fiber or synthetic materials, or any combination thereof. The packaging system comprises a movable insert that can locked in an inaccessible position and comprises a physically detachable unlocking mechanism that can engage the locking mechanism of the movable insert in order to unlock the movable insert permitting movement into an accessible position. The unlocking mechanism can be in the form of an access card that is a part of the system or is user supplied.