发明申请
US20070054862A1 Methods of Identifying Compounds that Modulate IL-4 Receptor-Mediated IgE Synthesis Utilizing an Adenosine Kinase
审中-公开
鉴定使用腺苷激酶调节IL-4受体介导的IgE合成的化合物的方法
- 专利标题: Methods of Identifying Compounds that Modulate IL-4 Receptor-Mediated IgE Synthesis Utilizing an Adenosine Kinase
- 专利标题(中): 鉴定使用腺苷激酶调节IL-4受体介导的IgE合成的化合物的方法
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申请号: US11550731申请日: 2006-10-18
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公开(公告)号: US20070054862A1公开(公告)日: 2007-03-08
- 发明人: Esteban Masuda , Todd Kinsella , Justin Warner , Taisei Kinoshita , Mark Bennett , David Anderson
- 申请人: Esteban Masuda , Todd Kinsella , Justin Warner , Taisei Kinoshita , Mark Bennett , David Anderson
- 申请人地址: US CA South San Francisco
- 专利权人: Rigel Pharmaceuticals, Inc.
- 当前专利权人: Rigel Pharmaceuticals, Inc.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: C07K14/47
- IPC分类号: C07K14/47 ; A61K38/16
摘要:
The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds that utilize an adenosine kinase as a surrogate analyte and methods of using the compounds in a variety of in vitro, in vitro and ex vivo contexts.
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