发明申请
- 专利标题： ESZOPICLONE PROCESS
- 专利标题（中）： ESZOPICLONE工艺
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申请号： US11469920申请日： 2006-09-05
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公开(公告)号： US20070054914A1公开(公告)日： 2007-03-08
- 发明人: Venkata Naga Brahmeswara Mandava , Sreenadhacharyulu Kandala , Mukunda Jambula , Raveendra Chinta
- 申请人： Venkata Naga Brahmeswara Mandava , Sreenadhacharyulu Kandala , Mukunda Jambula , Raveendra Chinta
- 优先权： IN1241/CHE/2005 20050905; IN1806/CHE/2005 20051209; IN1064/CHE/2006 20060622
- 主分类号： C07D487/02
- IPC分类号： C07D487/02 ; A61K31/496
摘要：
Eszopiclone is prepared by reacting zopiclone with an enatiomerically pure di-p-toluoyl tartaric acid, recovering a solid salt, and reacting a solid salt with a base. Zopiclone is prepared by reacting 6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]-pyrazine with 1-chlorocarbonyl-4-methylpiperazine hydrochloride.
公开/授权文献
- US07476737B2 Eszopiclone process 公开/授权日：2009-01-13
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