发明申请
US20070056049A1 p53 and VEGF regulate tumor growth of NOS2 expressing cancer cells
审中-公开
p53和VEGF调节NOS2表达癌细胞的肿瘤生长
- 专利标题： p53 and VEGF regulate tumor growth of NOS2 expressing cancer cells
- 专利标题（中）： p53和VEGF调节NOS2表达癌细胞的肿瘤生长
-
申请号： US11195006申请日： 2005-08-01
-
公开(公告)号： US20070056049A1公开(公告)日： 2007-03-08
- 发明人: Stefan Ambs , Curtis Harris
- 申请人： Stefan Ambs , Curtis Harris
- 申请人地址： US MD Rockville
- 专利权人： The Govt. of the USA as represented by the Secretary of the Dept. of Health & Human Services
- 当前专利权人： The Govt. of the USA as represented by the Secretary of the Dept. of Health & Human Services
- 当前专利权人地址： US MD Rockville
- 主分类号： A61K49/00
- IPC分类号： A61K49/00 ; G01N33/53 ; A61K31/198 ; A61K31/195
摘要：
The invention provides, for example, in vitro and in vivo methods for screening modulators of NOS-2 activity using p53 mutant cells, methods of predicting the benefit of administering NOS-2 inhibitors to a cancer patient, and methods of treating cancer by administering NOS-2 inhibitors to patients with p53 mutant cancers.
信息查询
