A tank manifold assembly for use in combination with fuel tanks of Hydrogen fuel cell-powered vehicles. The manifold assembly incorporates a regulator, an excess flow valve, a manual shutoff valve, and ports to receive separate components. The separate components may include, by way of example, a thermal relief valve, a pressure sensor, a pressure relief valve, a check valve, thermal temperature sensors, and a low pressure solenoid valve. The tank assembly is versatile and easily customized to particular applications.