Invention Application
- Patent Title: Polyethylene glycol/polycation block copolymers
- Patent Title (中): 聚乙二醇/聚阳离子嵌段共聚物
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Application No.: US10556058Application Date: 2004-05-07
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Publication No.: US20070059271A1Publication Date: 2007-03-15
- Inventor: Kazunori Kataoka , Naoki Kanayama , Keiji Itaka , Shigeto Fukushima , Atsushi Harada
- Applicant: Kazunori Kataoka , Naoki Kanayama , Keiji Itaka , Shigeto Fukushima , Atsushi Harada
- Applicant Address: JP SAITAMA
- Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
- Current Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
- Current Assignee Address: JP SAITAMA
- Priority: JP2003-130520 20030508; JP2003-315858 20030908
- International Application: PCT/JP04/06488 WO 20040507
- Main IPC: A61K31/787
- IPC: A61K31/787 ; C08L71/02
Abstract:
The invention provides block copolymers formed of poly(ethylene glycol) segments and poly(amino acid derivative) segments having side chains of at least one kind of specific amine residue. The invention also provides polyion complexes of such copolymers with polynucleotides and the like. These block copolymers are useful as carriers for in vivo delivery of active substances such as DNA.
Public/Granted literature
- US07780957B2 Polyethylene glycol/polycation block copolymers Public/Granted day:2010-08-24
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