发明申请
- 专利标题: Inhibitors of colony stimulating factors
- 专利标题(中): 抑制因子的集落刺激因子
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申请号: US11519502申请日: 2006-09-12
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公开(公告)号: US20070059280A1公开(公告)日: 2007-03-15
- 发明人: Madhav Devalaraja , Joseph Low
- 申请人: Madhav Devalaraja , Joseph Low
- 专利权人: Warner-Lambert Company LLC
- 当前专利权人: Warner-Lambert Company LLC
- 主分类号: A61K38/20
- IPC分类号: A61K38/20 ; A61K38/19 ; A61K39/395
摘要:
A hematopoetic factor called “colony stimulating factor” (CSF) is capable of synergizing the attracting capabilities of chemokines and of inducing the accumulation and/or activation in vitro and in vivo of key components of inflammatory responses. Various types of agents that inhibit or otherwise hinder the production, release or activity of CSF could be used therapeutically in the treatment of ischemia and other inflammatory diseases, such as autoimmune disease, and various chronic inflammatory diseases such as rheumatoid arthritis and psoriasis.
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