发明申请
- 专利标题: Triaza-cyclopenta [cd] indene derivatives
- 专利标题(中): 三氮杂 - 环戊二烯并[cd]茚衍生物
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申请号: US10584952申请日: 2005-01-06
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公开(公告)号: US20070060602A1公开(公告)日: 2007-03-15
- 发明人: Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo Kennis
- 申请人: Atsuro Nakazato , Taketoshi Okubo , Dai Nozawa , Tomoko Tamita , Ludo Kennis
- 优先权: JP2004-001312 20040106
- 国际申请: PCT/JP05/00323 WO 20050106
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; C07D487/14
摘要:
An object of the present invention is to provide an antagonist against CRF receptors which is effective as a therapeutic or prophylactic agent for diseases in which CRF is considered to be involved, such as depression, anxiety, Alzheimer's disease, Parkinson's disease, Huntington's chorea, eating disorder, hypertension, gastral diseases, drug dependence, epilepsy, cerebral infarction, cerebral ischemia, cerebral edema, cephalic external wound, inflammation, immunity-related diseases, alpecia, irritable bowel syndrome, sleep disorders, dermatitides, schizophrenia, pain, etc. A triaza-cyclopenta[cd]indene derivative represented by the following formula [I]: has a high affinity for CRF receptors and is effective against diseases in which CRF is considered to be involved.
公开/授权文献
- US07365078B2 Triaza-cyclopenta[cd]indene derivatives 公开/授权日:2008-04-29
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