发明申请
US20070065469A1 Liquid formulations with high concentration of human growth hormone (high) comprising glycine 审中-公开
具有高浓度人生长激素(高)的液体制剂,其包含甘氨酸

  • 专利标题: Liquid formulations with high concentration of human growth hormone (high) comprising glycine
  • 专利标题(中): 具有高浓度人生长激素(高)的液体制剂,其包含甘氨酸
  • 申请号: US10520570
    申请日: 2003-07-08
  • 公开(公告)号: US20070065469A1
    公开(公告)日: 2007-03-22
  • 发明人: Michael BetzJohn Stevens
  • 申请人: Michael BetzJohn Stevens
  • 优先权: US60394611 20020709; US60394612 20020709; US60394699 20020709
  • 国际申请: PCT/EP03/07346 WO 20030708
  • 主分类号: A61K38/27
  • IPC分类号: A61K38/27 A61K9/00
Liquid formulations with high concentration of human growth hormone (high) comprising glycine
摘要:
The present invention relates to liquid formulations of human growth hormone (hGH, somatropin) which are storage stable, show reduced or no crystallization on storage and are suitable for administration to the human or animal body. More particularly, the invention relates to liquid formulations of human growth hormone which are stable and exhibit minimal or no crystallization when stored at least for a time at temperatures above refrigeration temperatures.
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