发明申请
- 专利标题： Monocyclic and bicyclic compounds and methods of use
- 专利标题（中）： 单环和双环化合物及其使用方法
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申请号： US11504215申请日： 2006-08-14
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公开(公告)号： US20070066583A1公开(公告)日： 2007-03-22
- 发明人: Penglie Zhang , Andrew Pennell , John J. Wright , Lianfa Li , Edward Sullivan , Wei Chen , Kevin Lloyd Greenman
- 申请人： Penglie Zhang , Andrew Pennell , John J. Wright , Lianfa Li , Edward Sullivan , Wei Chen , Kevin Lloyd Greenman
- 申请人地址： US CA Mountain View
- 专利权人： ChemoCentryx, Inc.
- 当前专利权人： ChemoCentryx, Inc.
- 当前专利权人地址： US CA Mountain View
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; A61K31/506 ; A61K31/541 ; A61K31/5377 ; A61K31/496 ; A61K31/454 ; C07D417/02 ; C07D413/02 ; C07D403/02
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally monocyclic and bicyclic compounds and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
公开/授权文献
- US07790726B2 Monocyclic and bicyclic compounds and methods of use 公开/授权日：2010-09-07
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