发明申请
US20070066647A1 Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders
有权
构型受限的3-（4-羟基 - 苯基） - 取代 - 丙酸，可用于治疗代谢紊乱
- 专利标题： Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders
- 专利标题（中）： 构型受限的3-（4-羟基 - 苯基） - 取代 - 丙酸，可用于治疗代谢紊乱
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申请号： US11517992申请日： 2006-09-08
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公开(公告)号： US20070066647A1公开(公告)日： 2007-03-22
- 发明人: Michelle Akerman , Sean Brown , Jonathan Houze , Jinqian Liu , Jiwen Liu , Zhihua Ma , Julio Medina , Wei Qiu , Michael Schmitt , Rajiv Sharma , Yingcai Wang , Liusheng Zhu
- 申请人： Michelle Akerman , Sean Brown , Jonathan Houze , Jinqian Liu , Jiwen Liu , Zhihua Ma , Julio Medina , Wei Qiu , Michael Schmitt , Rajiv Sharma , Yingcai Wang , Liusheng Zhu
- 申请人地址： US CA Thousand Oaks
- 专利权人： AMGEN ING.
- 当前专利权人： AMGEN ING.
- 当前专利权人地址： US CA Thousand Oaks
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; A61K31/426 ; A61K31/353 ; A61K31/343 ; A61K31/192 ; A61K31/155
摘要：
The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I: where the definitions of the variables Q, L1, L2, M, X, L3, and A are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.