Various embodiments of a medical device (e.g., tissue acquisition device) having a separate hemostasis capability and related methods of use are disclosed. The device may include an elongated tubular member having a proximal end and a distal end, a tissue cutting member proximate the distal end of the tubular member, and a hemostatic member proximate the distal end of the tubular member and adjacent the tissue cutting member. At least one of the tissue cutting member and the hemostatic member may be fixedly connected to the tubular member.