Invention Application
US20070072302A1 Method for quantitatively determining the LDL particle number in a distribution of LDL cholesterol subfractions
审中-公开
定量测定低密度脂蛋白胆固醇分数分布中LDL粒子数的方法
- Patent Title: Method for quantitatively determining the LDL particle number in a distribution of LDL cholesterol subfractions
- Patent Title (中): 定量测定低密度脂蛋白胆固醇分数分布中LDL粒子数的方法
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Application No.: US11522591Application Date: 2006-09-18
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Publication No.: US20070072302A1Publication Date: 2007-03-29
- Inventor: Faith Clendenen , Christopher Boggess , Frank Ruderman
- Applicant: Faith Clendenen , Christopher Boggess , Frank Ruderman
- Assignee: Berkeley HeartLab, Inc.
- Current Assignee: Berkeley HeartLab, Inc.
- Main IPC: G01N33/92
- IPC: G01N33/92
Abstract:
The invention provides a method (e.g., a computer algorithm) for calculating a number of particles in a LDL subfraction. The method features the steps of: 1) measuring an initial distribution of LDL particles (e.g., a relative mass distribution) from a blood sample; 2) processing the initial distribution of LDL particles with a mathematical model to determine a modified distribution of LDL particles (e.g., a relative particle distribution); 3) determining a total LDL particle number value from a blood sample; and 4) analyzing both the modified distribution of particles and the total LDL particle number value to calculate the particle number value in an LDL subfraction.
Information query
IPC分类:
