The disclosed technology relates to a process for contacting a liquid phase and a second fluid phase, comprising: flowing the liquid phase and/or second fluid phase in a process microchannel in contact with surface features in the process microchannel, the contacting of the surface features with the liquid phase and/or second fluid phase imparting a disruptive flow to the liquid phase and/or second fluid phase; contacting the liquid phase with the second fluid phase in the process microchannel; and transferring mass from the liquid phase to the second fluid phase and/or from the second fluid phase to the liquid phase.