发明申请
- 专利标题： Piperidine derivatives and methods of use
- 专利标题（中）： 哌啶衍生物和使用方法
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申请号： US11546938申请日： 2006-10-11
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公开(公告)号： US20070088036A1公开(公告)日： 2007-04-19
- 发明人: Penglie Zhang , Andrew Pennell , Wei Chen , Kevin Greenman , Lianfa Li , Edward Sullivan
- 申请人： Penglie Zhang , Andrew Pennell , Wei Chen , Kevin Greenman , Lianfa Li , Edward Sullivan
- 申请人地址： US CA Mountain View
- 专利权人： ChemoCentryx, Inc.
- 当前专利权人： ChemoCentryx, Inc.
- 当前专利权人地址： US CA Mountain View
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61K31/498 ; A61K31/503 ; C07D498/02 ; C07D491/02 ; C07D487/02
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally monocyclic and bicyclic compounds and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
公开/授权文献
- US07576218B2 4-phenylpiperdine-pyrazole CCR1 antagonists 公开/授权日：2009-08-18
信息查询
IPC分类:
