- 专利标题: Biphenyl derivatives
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申请号: US11604607申请日: 2006-11-27
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公开(公告)号: US20070088054A1公开(公告)日: 2007-04-19
- 发明人: Mathai Mammen , Adam Hughes , Eric Stangeland , Yan Chen
- 申请人: Mathai Mammen , Adam Hughes , Eric Stangeland , Yan Chen
- 主分类号: C07D211/54
- IPC分类号: C07D211/54 ; C07D211/06 ; A61K31/445
摘要:
This invention provides biphenyl derivatives of formula I: wherein R1, R2, R3, R4, R5, R6, R7, W, a, b and c are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The biphenyl derivatives of this invention possess both β2 adrenergic receptor agonist and muscarinic receptor antagonist activity and therefore, such biphenyl derivatives are useful for treating pulmonary disorders, such as chronic obstructive pulmonary disease and asthma.
公开/授权文献
- US07514558B2 Biphenyl derivatives 公开/授权日:2009-04-07