Invention Application
- Patent Title: SUBSTITUTED PIPERAZINES AND PIPERIDINES AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR
- Patent Title (中): 作为神经元Y2受体的调节剂的替代哌嗪和哌啶
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Application No.: US11553556Application Date: 2006-10-27
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Publication No.: US20070100141A1Publication Date: 2007-05-03
- Inventor: Pascal Bonaventure , Nicholas Carruthers , Wenying Chai , Curt Dvorak , Jill Jablonowski , Dale Rudolph , Mark Seierstad , Chandravadan Shah , Devin Swanson , Victoria Wong
- Applicant: Pascal Bonaventure , Nicholas Carruthers , Wenying Chai , Curt Dvorak , Jill Jablonowski , Dale Rudolph , Mark Seierstad , Chandravadan Shah , Devin Swanson , Victoria Wong
- Main IPC: C07D413/02
- IPC: C07D413/02 ; C07D403/02 ; C07D401/02
Abstract:
The invention provides novel non-peptidic NPY Y2 receptor inhibitors useful in treating or preventing: anxiolytic disorders or depression; injured mammalian nerve tissue; conditions responsive to treatment through administration of a neurotrophic factor; neurological disorders; bone loss; substance related disorders; sleep/wake disorders; cardiovascular disease; obesity; or an obesity-related disorder. Compounds of the invention are also useful in modulating endocrine functions, particularly endocrine functions controlled by the pituitary and hypothalamic glands, and are therefore useful in the treatment or prevention of inovulation and infertility.
Public/Granted literature
- US08183239B2 Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor Public/Granted day:2012-05-22
Information query
