- 专利标题: PROCESS FOR REMOVING FARNESOL FROM MIXTURES WITH ALPHA-BISABOLOL
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申请号: US11553770申请日: 2006-10-27
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公开(公告)号: US20070100160A1公开(公告)日: 2007-05-03
- 发明人: Marcus Betzer , Walter Kuhn , Burghard Wilkening , Dietmar Schatkowski , Oskar Koch
- 申请人: Marcus Betzer , Walter Kuhn , Burghard Wilkening , Dietmar Schatkowski , Oskar Koch
- 优先权: DE102005051903.2 20051029
- 主分类号: C07C69/02
- IPC分类号: C07C69/02 ; C07C35/18
摘要:
Process for esterification of farnesol in an initial mixture comprising alpha-bisabolol, farnesol and optionally other components, with the following steps: 1. Preparation or production of the initial mixture, 2. Adding (i) a transesterification catalyst and (ii) one or more compounds of formula (B) R2YnCO2R1 (B) in which the following applies: R1 stands for an alkyl residue with 1 to 12 C atoms; R2 stands for hydrogen, an alkyl residue with 1 to 20 C atoms, a cycloalkyl residue with 5 to 20 C atoms, an aryl residue with 6 to 20 C atoms or a heteroaryl residue with 5 to 20 C atoms; and Y stands for CH2, CH(Me), CH(Et), C(Me)2, CH2—CH(Me), CH(Me)-CH2 or CH2—CH(Me)-CH2 and n stands for a whole number from 0 to 6; or R2 stands for a group CO2R3, R3 standing for an alkyl residue with 1 to 12 C atoms; and Y stands for CH2, CH(Me), CH(Et), C(Me)2, CH2—CH(Me), CH(Me)-CH2 or CH2—CH(Me)-CH2 and n stands for a whole number from 0 to 8, or Y stands for an optionally substituted phenyl or naphthyl ring with a total of at most four substituents on the ring, n=1 applying.
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