发明申请
- 专利标题： Pyrimidine derivatives for treatment of hyperproliferative disorders
- 专利标题（中）： 嘧啶衍生物用于治疗过度增殖性疾病
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申请号： US10573227申请日： 2004-10-08
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公开(公告)号： US20070117817A1公开(公告)日： 2007-05-24
- 发明人: Julie Dixon , Dhanapalan Nagarathnam , Lei Zhang , Chunguang Wang , Lin Yin , Yuanwei Chen , Jianqing Chen , Brian Bear , Michael Brands , Alexander Hillisch , Donald Bierer , Ming Wang , Wenlang Fu , Martin Hentemann , Ann-Marie Bullion
- 申请人： Julie Dixon , Dhanapalan Nagarathnam , Lei Zhang , Chunguang Wang , Lin Yin , Yuanwei Chen , Jianqing Chen , Brian Bear , Michael Brands , Alexander Hillisch , Donald Bierer , Ming Wang , Wenlang Fu , Martin Hentemann , Ann-Marie Bullion
- 申请人地址： US CT West Haven 06516
- 专利权人： Bayer Pharmaceuticals Corporation
- 当前专利权人： Bayer Pharmaceuticals Corporation
- 当前专利权人地址： US CT West Haven 06516
- 优先权： US60/510804 20031010
- 国际申请： PCT/US04/33430 WO 20041008
- 主分类号： A61K31/513
- IPC分类号： A61K31/513 ; A61K31/506 ; C07D403/02
摘要：
Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G′, and G″ represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.