Disclosed is a hybrid wireless communication system and a communication method in the system. The system supports time and frequency division duplexing modes and includes a base station having a cellular communication range based on a cellular mode and mobile stations within the cellular communication range. The base station divides each available frequency resource into frames for communication, and each frame switches between a real-time service mode and a non-real-time service mode at a switching time within the frame. Communication is performed with the mobile stations within the cellular communication range via at least one of an uplink and a downlink in the real-time service mode of each frame according to the frequency division duplexing mode. Communication is performed with the mobile stations via the uplink and the downlink in the non-real-time service mode of each frame according to an ad hoc mode based on the time division duplexing mode.