发明申请
- 专利标题： Preparation method of a hair dermal papilla cell preparation, composition and method for regenerating hair follicles, and animal having regenerated hair follicles
- 专利标题（中）： 毛发真皮乳头细胞制剂的制备方法，再生毛囊的组合物和方法以及具有再生毛囊的动物
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申请号： US10574697申请日： 2004-09-30
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公开(公告)号： US20070122386A1公开(公告)日： 2007-05-31
- 发明人: Jiro Kishimoto , Ritsuko Ehama , Ritsuro Ideta , Takayuki Arai , Kiichiro Yano , Tsutomu Soma
- 申请人： Jiro Kishimoto , Ritsuko Ehama , Ritsuro Ideta , Takayuki Arai , Kiichiro Yano , Tsutomu Soma
- 申请人地址： JP Tokyo 104-8010
- 专利权人： Shiseido Company, Ltd.
- 当前专利权人： Shiseido Company, Ltd.
- 当前专利权人地址： JP Tokyo 104-8010
- 优先权： JP2003-346937 20031006; JP2003-346939 20031006; JP2004-048322 20040224
- 国际申请： PCT/JP04/14779 WO 20040930
- 主分类号： A61K35/36
- IPC分类号： A61K35/36 ; C12N5/06 ; C12N5/08
摘要：
The present invention provides a method for preparing a hair dermal papilla cell preparation comprising preparing a cell suspension by removing epidermal tissue from skin tissue and subjecting the resulting dermal tissue fraction to collagenase treatment, and cyropreserving the cell suspension to kill the follicular epidermal cells. The present invention also provides a composition for regenerating hair follicles comprising hair dermal papilla cell and epidermal cells, wherein the ratio of the number of hair dermal papilla cell to the number of epidermal cells is from 1:10 to 10:1.
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