发明申请
US20070122811A1 Compositions and processes for genotyping single nucleotide polymorphisms
审中-公开
基因分型单核苷酸多态性的组成和过程
- 专利标题： Compositions and processes for genotyping single nucleotide polymorphisms
- 专利标题（中）： 基因分型单核苷酸多态性的组成和过程
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申请号： US10574551申请日： 2004-09-30
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公开(公告)号： US20070122811A1公开(公告)日： 2007-05-31
- 发明人: Philip Buzby
- 申请人： Philip Buzby
- 国际申请： PCT/US04/32164 WO 20040930
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34 ; C12N9/16
摘要：
The invention relates to processes, compositions and kits for analysis of nucleic acid variations, especially single nucleotide polymorphisms (SNPs). An inventive process includes a procedure to enzymatically remove inorganic pyrophosphate from a sample prior to and/or during a single base extension reaction. Processes and compositions described herein are especially useful in nucleic acid analysis methods designed to minimize transfer and separation steps.