发明申请
- 专利标题： Method of selecting novel immunosuppressant
- 专利标题（中）： 选择新型免疫抑制剂的方法
-
申请号： US10540546申请日： 2003-12-26
-
公开(公告)号： US20070123452A1公开(公告)日： 2007-05-31
- 发明人: Hideaki Matsuoka , Takao Fujimura , Masako Hayashi , Ichiro Aramori
- 申请人： Hideaki Matsuoka , Takao Fujimura , Masako Hayashi , Ichiro Aramori
- 申请人地址： JP Tokyo 103-8411
- 专利权人： Astellas Pharma Inc.
- 当前专利权人： Astellas Pharma Inc.
- 当前专利权人地址： JP Tokyo 103-8411
- 优先权： JP2002-378800 20021227
- 国际申请： PCT/JP03/16895 WO 20031226
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K38/12 ; A61K31/19 ; C12Q1/34
摘要：
The present invention provides a method of selecting an IL-2 production inhibitor and/or an immunocyte proliferation inhibitor having low GATA-1 production inhibitory activity, which comprises measuring the HDAC4 and/or HDAC8 inhibitory activity of a test substance, and a method of selecting an immunosuppressant having low thrombocytopenic activity, which comprises measuring the HDAC4 and/or HDAC8 inhibitory activity of a test HDAC inhibitor.
信息查询
