Invention Application
US20070123475A1 WATER-SOLUBLE ETOPOSIDE ANALOGS AND METHODS OF USE THEREOF
失效
水溶性ETOPOSIDE ANALOGS及其使用方法
- Patent Title: WATER-SOLUBLE ETOPOSIDE ANALOGS AND METHODS OF USE THEREOF
- Patent Title (中): 水溶性ETOPOSIDE ANALOGS及其使用方法
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Application No.: US11619304Application Date: 2007-01-03
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Publication No.: US20070123475A1Publication Date: 2007-05-31
- Inventor: Kuo-Hsiung Lee , Zhiyan Xiao , Kenneth Bastow
- Applicant: Kuo-Hsiung Lee , Zhiyan Xiao , Kenneth Bastow
- Main IPC: A61K31/7048
- IPC: A61K31/7048 ; A61K31/365 ; C07D493/02
Abstract:
Etoposide analogs with improved water-solubility such as 4′-O-Demethyl-4′-(N′,N′-dimethyl-glycyl)-4β-(4″-nitroanilino)-4-desoxy-podophyllotoxin (8) and 4′-O-Demethyl-4′-(N′,N′-dimethyl-glycyl)-4β-(4″-fluoroanilino)-4-desoxy-podophyllotoxin (9) are described, along with pharmaceutical formulations containing the same, methods of use thereof, and intermediates and methods of making the same.
Public/Granted literature
- US07671088B2 Water-soluble etoposide analogs and methods of use thereof Public/Granted day:2010-03-02
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