发明申请
US20070128603A1 Diagnostic and therapeutics for diseases associated with 5-hydroxytryptamine (serotonin) receptor 7 (5-ht7)
审中-公开
与5-羟色胺（5-羟色胺）受体7（5-ht7）相关的疾病的诊断和治疗
- 专利标题： Diagnostic and therapeutics for diseases associated with 5-hydroxytryptamine (serotonin) receptor 7 (5-ht7)
- 专利标题（中）： 与5-羟色胺（5-羟色胺）受体7（5-ht7）相关的疾病的诊断和治疗
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申请号： US10558297申请日： 2004-05-15
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公开(公告)号： US20070128603A1公开(公告)日： 2007-06-07
- 发明人: Stefan Golz , Ulf Bruggemeier , Andreas Geerts
- 申请人： Stefan Golz , Ulf Bruggemeier , Andreas Geerts
- 申请人地址： DE Leverkusen D-51368
- 专利权人： BAYER HEALTHCARE AG
- 当前专利权人： BAYER HEALTHCARE AG
- 当前专利权人地址： DE Leverkusen D-51368
- 优先权： EP03011961.4 20030528
- 国际申请： PCT/EP04/05255 WO 20040515
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G01N33/574
摘要：
The invention provides a human 5-HT7 which is associated with the cardiovascular disorders, dermatological disorders, gastrointestinal and liver diseases, cancer disorders, inflammatory diseases, metabolic diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular disorders, dermatological disorders, gastrointestinal and liver diseases, cancer disorders, inflammatory diseases, metabolic diseases, hematological disorders, respiratory diseases, neurological disorders and urological disorders. The invention also features compounds which bind to and/or activate or inhibit the activity of 5-HT7 as well as pharmaceutical compositions comprising such compounds.
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