发明申请
- 专利标题： Method for the separation of intermediates which may be used for the preparation of escitalopram
- 专利标题（中）： 用于分离可用于制备依他普仑的中间体的方法
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申请号： US10524937申请日： 2003-08-12
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公开(公告)号： US20070129561A1公开(公告)日： 2007-06-07
- 发明人: Naoki Taoka , Takahisa Kato , Shogo Yamamoto , Takashi Yoshida , Toshihiro Takeda , Yasuyoshi Ueda , Hans Petersen , Robert Dancer , Haleh Ahmadian , Lars Lyngso
- 申请人： Naoki Taoka , Takahisa Kato , Shogo Yamamoto , Takashi Yoshida , Toshihiro Takeda , Yasuyoshi Ueda , Hans Petersen , Robert Dancer , Haleh Ahmadian , Lars Lyngso
- 优先权： DKPA200201201 20020812
- 国际申请： PCT/DK03/00537 WO 20030812
- 主分类号： C07C323/20
- IPC分类号： C07C323/20 ; C07C271/40 ; C12P13/00 ; C12P7/22
摘要：
The present invention relates to a novel method for the preparation of diol intermediates having the formula (II) and/or the opposite enantiomer of an acylated diol having the formula (IV) useful for the preparation of escitalopram involving selective enzymatic acylation or deacylation.
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