A transmitter and a transmitting method in a code division multiplexing (CDM) wireless communication system are provided. The transmitter includes a DC offset unit, a Barker code generating unit, a multiplier, a unipolar code generating unit, a Kronecker product unit, and a modulator. The DC offset unit transforms digital transmitting data to bipolar data, and the Barker code generating unit generates a Barker code. The multiplier multiplies the bipolar data with the Barker code and outputting the multiplying result, and the unipolar code generating unit generates a predetermined unipolar code. The Kronecker product unit multiplies the multiplying result from the multiplier and the unipolar code based on the Kronecker product, and outputs the result thereof, and the modulator modulates the output of the Kronecker produce unit through the On-Off keying modulation scheme.