发明申请
- 专利标题： INJECTABLE CARRIER FORMULATIONS OF HYALURONIC ACID DERIVATIVES FOR DELIVERY OF OSTEOGENIC PROTEINS
- 专利标题（中）： 用于递送蛋白质的羟丙酸衍生物的可手动载体配方
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申请号： US11624463申请日： 2007-01-18
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公开(公告)号： US20070134342A1公开(公告)日： 2007-06-14
- 发明人: Hyun Kim , Rebecca Li , Alessandra Pavesio , Lanfranco Callegaro , Howard Seeherman , John Wozney
- 申请人： Hyun Kim , Rebecca Li , Alessandra Pavesio , Lanfranco Callegaro , Howard Seeherman , John Wozney
- 专利权人： Genetics Institute, Inc.,Fidia Advanced Biopolymers S.R.L.
- 当前专利权人： Genetics Institute, Inc.,Fidia Advanced Biopolymers S.R.L.
- 主分类号： A61K38/18
- IPC分类号： A61K38/18 ; A61K31/728 ; A61K9/14
摘要：
An injectable formulation is disclosed for delivery of osteogenic proteins. The formulation comprises a pharmaceutically acceptable admixture of an osteogenic protein; and formulations comprising osteogenic protein, hyaluronic acid derivatives and tricalcium phosphate are also disclosed. Methods for formulating porous injectable gels and pastes from hyaluronic acid are also disclosed.
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