发明申请
US20070134688A1 CALCULATED INDEX OF GENOMIC EXPRESSION OF ESTROGEN RECEPTOR (ER) AND ER-RELATED GENES
审中-公开
雌激素受体（ER）和ER相关基因的基因表达的计算指数
- 专利标题： CALCULATED INDEX OF GENOMIC EXPRESSION OF ESTROGEN RECEPTOR (ER) AND ER-RELATED GENES
- 专利标题（中）： 雌激素受体（ER）和ER相关基因的基因表达的计算指数
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申请号： US11530785申请日： 2006-09-11
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公开(公告)号： US20070134688A1公开(公告)日： 2007-06-14
- 发明人: W. Fraser Symmans , Christos Hatzis , Keith Anderson , Lajos Pusztai
- 申请人： W. Fraser Symmans , Christos Hatzis , Keith Anderson , Lajos Pusztai
- 专利权人： THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM,NUVERA BIOSCIENCES, INC.
- 当前专利权人： THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM,NUVERA BIOSCIENCES, INC.
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G01N33/574 ; A61K31/56
摘要：
The present invention provides the identification and combination of genes that are expressed in tumors that are responsive to a given therapeutic agent and whose combined expression can be used as an index that correlates with responsiveness to that therapeutic agent. One or more of the genes of the present invention may be used as markers (or surrogate markers) to identify tumors that are likely to be successfully treated by that agent or class of agents such as hormonal or endocrine treatment.
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