发明申请
US20070134749A1 Protein tyrosine kinase substrate lat and its use in the identification of (ANT)agonists of the kinase
审中-公开
蛋白酪氨酸激酶底物及其用于鉴定激酶的（ANT）激动剂
- 专利标题： Protein tyrosine kinase substrate lat and its use in the identification of (ANT)agonists of the kinase
- 专利标题（中）： 蛋白酪氨酸激酶底物及其用于鉴定激酶的（ANT）激动剂
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申请号： US11607719申请日： 2006-12-01
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公开(公告)号： US20070134749A1公开(公告)日： 2007-06-14
- 发明人: Lawrence Samelson , Weiguo Zhang
- 申请人： Lawrence Samelson , Weiguo Zhang
- 申请人地址： US MD Rockville
- 专利权人： Government of the US, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人： Government of the US, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人地址： US MD Rockville
- 优先权： USPCT/US98/27400 19981223
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07H21/04 ; C12N9/12 ; C07K16/40
摘要：
The invention generally relates to compositions and methods for identifying and testing tyrosine kinase signaling pathway agonists and antagonists, and more particularly, methods and compositions for screening compounds and identifying compounds that will modulate the interaction of protein tyrosine kinase substrates with their intracellular ligands, as well as between their intracellular ligands and other members of the signaling pathway.