发明申请
US20070135350A1 Methods of Identifying Compounds that Modulate IL-4 Receptor-Mediated IgE Synthesis Utilizing a B-Cell Associated Protein
审中-公开
鉴定使用B细胞相关蛋白调节IL-4受体介导的IgE合成的化合物的方法
- 专利标题: Methods of Identifying Compounds that Modulate IL-4 Receptor-Mediated IgE Synthesis Utilizing a B-Cell Associated Protein
- 专利标题(中): 鉴定使用B细胞相关蛋白调节IL-4受体介导的IgE合成的化合物的方法
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申请号: US11676802申请日: 2007-02-20
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公开(公告)号: US20070135350A1公开(公告)日: 2007-06-14
- 发明人: Esteban Masuda , Todd Kinsella , Justin Warner , Taisei Kinoshita , Mark Bennett , David Anderson
- 申请人: Esteban Masuda , Todd Kinsella , Justin Warner , Taisei Kinoshita , Mark Bennett , David Anderson
- 申请人地址: US CA South San Francisco
- 专利权人: Rigel Pharmaceuticals, Inc.
- 当前专利权人: Rigel Pharmaceuticals, Inc.
- 当前专利权人地址: US CA South San Francisco
- 主分类号: A61K38/10
- IPC分类号: A61K38/10 ; C07K7/08
摘要:
The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds that utilize a BAP-37 as a surrogate analyte and methods of using the compounds in a variety of in vitro, in vitro and ex vivo contexts.
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