发明申请
US20070135417A1 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles,and chromones and preparation and uses thereof
失效
1H-吲唑，苯并噻唑，1,2-苯并异恶唑，1,2-苯并异噻唑和色酮及其制备和用途
- 专利标题： 1H-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles,and chromones and preparation and uses thereof
- 专利标题（中）： 1H-吲唑，苯并噻唑，1,2-苯并异恶唑，1,2-苯并异噻唑和色酮及其制备和用途
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申请号： US11594993申请日： 2006-11-09
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公开(公告)号： US20070135417A1公开(公告)日： 2007-06-14
- 发明人: Richard Schumacher , Jianguo Ma , Brian Herbert , Mihaela Danca , Wenge Xie , Truc Nguyen , Ashok Tehim
- 申请人： Richard Schumacher , Jianguo Ma , Brian Herbert , Mihaela Danca , Wenge Xie , Truc Nguyen , Ashok Tehim
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; C07D487/04 ; A61K31/498
摘要：
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
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