发明申请
- 专利标题： Benzoylguanidlne salt and hydrates thereof
- 专利标题（中）： 苯甲酰胍基盐及其水合物
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申请号： US11649632申请日： 2007-01-04
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公开(公告)号： US20070135446A1公开(公告)日： 2007-06-14
- 发明人: Christian Elckmeier , Peter Sieger , Werner Rall , Volkmar Koerner , Rolf Herter
- 申请人： Christian Elckmeier , Peter Sieger , Werner Rall , Volkmar Koerner , Rolf Herter
- 申请人地址： DE Ingelheim
- 专利权人： Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人： Boehringer Ingelheim Pharma GmbH & Co. KG
- 当前专利权人地址： DE Ingelheim
- 优先权： DE10106970 20010215
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D403/02
摘要：
4-[4-(2-pyrrolylcarbonyl)-1-piperazinyl]-3-trifluoromethylbenzoylguanidine hydrochloride and its hydrates, processes for preparing this benzoylguanidine salt and its hydrates, pharmaceutical compositions containing this benzoylguanidine salt and its hydrates, and its use in treating diseases, particularly those in which inhibition of the cellular Na+/H+exchange is of therapeutic benefit.