发明申请
US20070142430A1 SUBSTITUTED TETRAHYDRO-2H-ISOQUINOLIN-1-ONE DERIVATIVES, AND METHODS FOR THE PRODUCTION AND USE THEREOF
失效
取代的四氢-2H-异喹啉-1-酮衍生物及其生产和使用方法
- 专利标题： SUBSTITUTED TETRAHYDRO-2H-ISOQUINOLIN-1-ONE DERIVATIVES, AND METHODS FOR THE PRODUCTION AND USE THEREOF
- 专利标题（中）： 取代的四氢-2H-异喹啉-1-酮衍生物及其生产和使用方法
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申请号： US11567352申请日： 2006-12-06
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公开(公告)号： US20070142430A1公开(公告)日： 2007-06-21
- 发明人: Stefan PEUKERT , Stefan GUESSREGEN , Armin HOFMEISTER , Herman SCHREUDER , Uwe SCHWAHN
- 申请人： Stefan PEUKERT , Stefan GUESSREGEN , Armin HOFMEISTER , Herman SCHREUDER , Uwe SCHWAHN
- 申请人地址： DE Frankfurt am Main
- 专利权人： sanofi-aventis Deutschland GmbH
- 当前专利权人： sanofi-aventis Deutschland GmbH
- 当前专利权人地址： DE Frankfurt am Main
- 优先权： DE102004028973.5 20040616
- 主分类号： A61K31/47
- IPC分类号： A61K31/47 ; C07D217/22
摘要：
This invention relates to compounds according to the general formula (I), where the definitions of the substituents R1, R2, Ar and X are as specified in the description, and to their physiologically tolerated salts, methods for the preparation of these compounds and their use as medicaments. These compounds are poly(ADP-ribose) polymerase (PARP) inhibitors.
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