发明申请
US20070149616A1 C3-Convertase Inhibitors for the Prevention and Treatment of Age-Related Macular Degeneration in Patients With At Risk Variants Of Complement Factor H
审中-公开
用于预防和治疗患有年龄相关性黄斑变性的C3-转化酶抑制剂在患有风险变异的补体因子H
- 专利标题： C3-Convertase Inhibitors for the Prevention and Treatment of Age-Related Macular Degeneration in Patients With At Risk Variants Of Complement Factor H
- 专利标题（中）： 用于预防和治疗患有年龄相关性黄斑变性的C3-转化酶抑制剂在患有风险变异的补体因子H
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申请号： US11614595申请日： 2006-12-21
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公开(公告)号： US20070149616A1公开(公告)日： 2007-06-28
- 发明人: Abbot Clark , Allan Shepard
- 申请人： Abbot Clark , Allan Shepard
- 申请人地址： US TX Fort Worth
- 专利权人： Alcon Manufacturing, Ltd.
- 当前专利权人： Alcon Manufacturing, Ltd.
- 当前专利权人地址： US TX Fort Worth
- 主分类号： A61K31/235
- IPC分类号： A61K31/235 ; C12Q1/68
摘要：
The present invention provides methods for identifying a patient at risk for developing AMD by identifying the presence of the Y402H polymorphism or other at risk variants in the complement factor H gene. The present invention further provides methods for treating persons having AMD or at risk for developing AMD as a result of having the Y402H polymorphism or other at risk variants in the complement factor H gene.
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