发明申请
- 专利标题： RNAi modulation of HIF-1 and therapeutic uses thereof
- 专利标题（中）： HIF-1的RNAi调节及其治疗用途
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申请号： US11477028申请日： 2006-06-27
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公开(公告)号： US20070155686A1公开(公告)日： 2007-07-05
- 发明人: Akin Akinc , Antonin Fougerolles , Hans-Peter Vornlocher , Philipp Hadwiger
- 申请人： Akin Akinc , Antonin Fougerolles , Hans-Peter Vornlocher , Philipp Hadwiger
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07H21/02
摘要：
The features of the present invention relate to compounds, compositions and methods useful for modulating the expression of HIF-1α, such as by the mechanism of RNA interference (RNAi). The compounds and compositions include iRNA agents that can be unmodified or chemically-modified.
公开/授权文献
- US07737265B2 RNAi modulation of HIF-1 and therapeutic uses thereof 公开/授权日：2010-06-15