发明申请
US20070160657A1 Targeting and intestinal-absorption controlled liposome having sugar chain and therapeutic drug for cancer and diagnostic drug containing the liposome
审中-公开
具有糖链的靶向和肠道吸收控制的脂质体和用于癌症的治疗药物和含有脂质体的诊断药物
- 专利标题: Targeting and intestinal-absorption controlled liposome having sugar chain and therapeutic drug for cancer and diagnostic drug containing the liposome
- 专利标题(中): 具有糖链的靶向和肠道吸收控制的脂质体和用于癌症的治疗药物和含有脂质体的诊断药物
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申请号: US10566566申请日: 2004-07-30
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公开(公告)号: US20070160657A1公开(公告)日: 2007-07-12
- 发明人: Noboru Yamazaki , Hideo Tsurushima , Shuuji Kojima
- 申请人: Noboru Yamazaki , Hideo Tsurushima , Shuuji Kojima
- 申请人地址: JP Ibaraki 305-8565
- 专利权人: National Institute of Advanced Industrial Science
- 当前专利权人: National Institute of Advanced Industrial Science
- 当前专利权人地址: JP Ibaraki 305-8565
- 优先权: JP2003-285432 20030801; JP2004-093872 20040326
- 国际申请: PCT/JP04/11291 WO 20040730
- 主分类号: A61K9/127
- IPC分类号: A61K9/127 ; A61K31/739 ; C08B37/00
摘要:
An object of the present invention is to provide a liposome having a sugar chain bonded thereto, the sugar chain having an activity of specifically binding to various lectins (sugar chain recognizing proteins) present on the cell surfaces of various tissues and thus being capable of actually distinguishing a cell and a tissue in vivo, thereby efficiently delivering a medicinal drug or a gene.
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