发明申请
US20070160675A1 Nanoparticulate and controlled release compositions comprising a cephalosporin
审中-公开
包含头孢菌素的纳米颗粒和控释组合物
- 专利标题： Nanoparticulate and controlled release compositions comprising a cephalosporin
- 专利标题（中）： 包含头孢菌素的纳米颗粒和控释组合物
-
申请号： US11478891申请日： 2006-06-30
-
公开(公告)号： US20070160675A1公开(公告)日： 2007-07-12
- 发明人: John Devane , Paul Stark , Niall Fanning , Gurvinder Rekhi , Scott Jenkins , Gary Liversidge
- 申请人： John Devane , Paul Stark , Niall Fanning , Gurvinder Rekhi , Scott Jenkins , Gary Liversidge
- 申请人地址： IE Dublin
- 专利权人： Elan Corporation, plc
- 当前专利权人： Elan Corporation, plc
- 当前专利权人地址： IE Dublin
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K31/545
摘要：
The present invention provides a composition comprising cephalosporin useful in the treatment and prevention of a bacterial infection. In one embodiment, the composition comprises nanoparticulate particles comprising cephalosporin and at least one surface stabilizer. The nanoparticulate particles have an effective average particle size of less than about 2000 nm. In another embodiment, the composition comprises a modified release composition that, upon administration to a patient, delivers cephalosporin in a bimodal, multimodal or continuous manner. The invention also relates to dosage forms containing such compositions, and to methods for the treatment and prevention of a bacterial infection.
信息查询
