发明申请
- 专利标题： Modulation of survivin expression
- 专利标题（中）： 生存素表达调控
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申请号： US10559636申请日： 2004-06-03
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公开(公告)号： US20070161547A1公开(公告)日： 2007-07-12
- 发明人: Balkrishen Bhat , Bharvin Patel , Eric Swayze
- 申请人： Balkrishen Bhat , Bharvin Patel , Eric Swayze
- 优先权： US10618553 20030711; US10823448 20040413
- 国际申请： PCT/US04/17490 WO 20040603
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; C07H21/02
摘要：
Compounds and compositions are provided for modulating the expression of survivin. The compounds, exemplified by those acting through an RNAi antisense mechanism of action, include double-stranded and single-stranded constructs, as well as siRNAs, canonical siRNAs, blunt-ended siRNAs and single-stranded antisense RNA compounds. Methods of using these compounds for modulation of survivin expression and for treatment of diseases associated with expression of survivin are provided.
公开/授权文献
- US07541344B2 Modulation of survivin expression 公开/授权日：2009-06-02
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