发明申请
- 专利标题: Preparation of Isoxazolin-3-Ylacylbenzene
- 专利标题(中): 异恶唑啉-3-酰基苯的制备
-
申请号: US11684630申请日: 2007-03-11
-
公开(公告)号: US20070161800A1公开(公告)日: 2007-07-12
- 发明人: Joachim Rheinheimer , Wolfgang von Deyn , Joachim Gebhardt , Michael Rack , Rene Lochtman , Norbert Gotz , Michael Keil , Matthias Witschel , Helmut Hagen , Ulf Misslitz , Ernst Boumann
- 申请人: Joachim Rheinheimer , Wolfgang von Deyn , Joachim Gebhardt , Michael Rack , Rene Lochtman , Norbert Gotz , Michael Keil , Matthias Witschel , Helmut Hagen , Ulf Misslitz , Ernst Boumann
- 优先权: DE19820722.0 19980511; DE19852095.6 19981112
- 主分类号: C07D261/02
- IPC分类号: C07D261/02 ; C07C317/32
摘要:
A process is described for preparing isoxazoles of the formula I where the substituents are as defined below: R1 is hydrogen, C1-C6-alkyl, R2 is C1-C6-alkyl, R3, R4, R5 are hydrogen, C1-C6-alkyl, or R4 and R5 together form a bond, R6 is a heterocyclic ring, n is 0, 1 or 2; which comprises preparing an intermediate of the formula VI where R1, R3, R4 and R5 are as defined above, followed by halogenation, thiomethylation, oxidation and acylation to give compounds of the formula I. Also novel intermediates for preparing the compounds of the formula I and novel processes for preparing the intermediates are described.
公开/授权文献
- US07663001B2 Preparation of isoxazolin-3-ylacylbenzene 公开/授权日:2010-02-16
信息查询