发明申请
- 专利标题： Remedy for spinal canal stenosis
- 专利标题（中）： 椎管狭窄治疗
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申请号： US10551755申请日： 2004-04-02
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公开(公告)号： US20070167403A1公开(公告)日： 2007-07-19
- 发明人: Yoshifumi Takenobu , Yoshihisa Kamanaka , Takaaki Obata
- 申请人： Yoshifumi Takenobu , Yoshihisa Kamanaka , Takaaki Obata
- 优先权： JP2003-100388 20030403
- 国际申请： PCT/JP04/04836 WO 20040402
- 主分类号： A61K31/724
- IPC分类号： A61K31/724 ; A61K31/557 ; A61K31/045
摘要：
A remedy for spinal canal stenosis which comprises a combination of a compound having EP2 agonism with a compound having EP3 agonism. A drug comprising a combination of a compound having EP2 agonism with a compound having EP3 agonism shows an efficacy in a rat gait disorder model induced by compression of cauda equina. Namely, it is efficacious against spinal canal stenosis to use a combination of a compound having EP2 agonism with a compound having EP3 agonism or a compound having both EP2 agonism and EP3 agonism.
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