发明申请
US20070185151A1 Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT3 and neuronal nicotinic receptor antagonists
审中-公开
氨基环己烷NMDA，5HT3和神经元烟碱受体拮抗剂的Azabicyclic，azatricyclic和azaspirocyclic衍生物
- 专利标题： Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexane NMDA, 5HT3 and neuronal nicotinic receptor antagonists
- 专利标题（中）： 氨基环己烷NMDA，5HT3和神经元烟碱受体拮抗剂的Azabicyclic，azatricyclic和azaspirocyclic衍生物
-
申请号： US11732764申请日： 2007-04-04
-
公开(公告)号： US20070185151A1公开(公告)日： 2007-08-09
- 发明人: Christopher Parsons , Markus Henrich , Wojciech Danysz , Ivars Kalvinsh , Valerjans Kauss , Aigars Jirgensons , Markus Gold , Maksims Vanejevs
- 申请人： Christopher Parsons , Markus Henrich , Wojciech Danysz , Ivars Kalvinsh , Valerjans Kauss , Aigars Jirgensons , Markus Gold , Maksims Vanejevs
- 申请人地址： DE FRANKFURT MAIN
- 专利权人： MERZ PHARMA GMBH & CO. KGAA
- 当前专利权人： MERZ PHARMA GMBH & CO. KGAA
- 当前专利权人地址： DE FRANKFURT MAIN
- 主分类号： A61K31/44
- IPC分类号： A61K31/44
摘要：
Azabicyclic, azatricyclic and azaspirocyclic derivatives of aminocyclohexanes which are systemically-active as NMDA, 5HT3, and nicotinic receptor antagonists, pharmaceutical compostions comprising the same, method of preparation thereof, and method of treating CNS disorders which involve disturbances of glutamatergic, serotoninergic, and nicotinic transmission, treating immunomodulatory disorders, and antimalaria, antitrypanosomal, anti-Borna virus, anti-HSV and anti-Hepatitis C virus activity.
信息查询
