Apparatus, methods, computer program products and data structures are provided that enable effective in-band signaling and data structures for adaptive control and operation of segmentation. An exemplary method includes: determining, during an ongoing wireless communication, that a current communication scheme is to be changed to a new communication scheme including one of a new segmentation scheme or a new non-segmentation scheme; and sending a control protocol data unit (C-PDU) from a first device to a second device, wherein the C-PDU includes identification information identifying the new communication scheme and control information related to the new communication scheme.