发明申请
US20070196484A1 Poorly water-soluble drug-containing solid formulation 审中-公开
水溶性较差的含药固体制剂

  • 专利标题: Poorly water-soluble drug-containing solid formulation
  • 专利标题(中): 水溶性较差的含药固体制剂
  • 申请号: US10592122
    申请日: 2005-03-09
  • 公开(公告)号: US20070196484A1
    公开(公告)日: 2007-08-23
  • 发明人: Kaoru WadaShinji Ando
  • 申请人: Kaoru WadaShinji Ando
  • 优先权: JP2004-067877 20040310
  • 国际申请: PCT/JP05/04042 WO 20050309
  • 主分类号: A61K9/24
  • IPC分类号: A61K9/24 A61K31/255
Poorly water-soluble drug-containing solid formulation
摘要:
Even when being released in a region from a lower small intestine to a large intestine with various coatings, bisacodyl is inadequately effective because of its hardness to dissolve due to its poor solubility, and thus a more drug should be contained. In the related art, there have been no techniques for allowing bisacodyl and dioctyl sodium sulfosuccinate to be simultaneously released in a region from a lower small intestine to a large intestine. A solid formulation having a core particle containing bisacodyl and dioctyl sodium sulfosuccinate coated with an enteric coating which allows the drugs to be released in a region from a lower small intestine to a large intestine can be used as an excellent pharmaceutical product.
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