- 专利标题: Certain chemical entities, compositions and methods
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申请号: US11639398申请日: 2006-12-13
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公开(公告)号: US20070197504A1公开(公告)日: 2007-08-23
- 发明人: Bradley Morgan , Alex Muci , Erica Kraynack , Todd Tochimoto , Pu-Ping Lu , David Morgans
- 申请人: Bradley Morgan , Alex Muci , Erica Kraynack , Todd Tochimoto , Pu-Ping Lu , David Morgans
- 主分类号: A61K31/551
- IPC分类号: A61K31/551 ; A61K31/55 ; A61K31/541 ; A61K31/5377 ; A61K31/496 ; A61K31/497 ; A61K31/506 ; A61K31/501 ; C07D417/02 ; C07D413/02 ; C07D403/02
摘要:
Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
公开/授权文献
- US07825120B2 Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas 公开/授权日:2010-11-02
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